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Entries in biodesign (2)

Thursday
Nov152007

Monkey See, Monkey Duplicate

Researchers get stem cells from cloned monkeys.
clipped from www.reuters.com
Photo

U.S. researchers have cloned monkeys and used the resulting embryos to get embryonic stem cells, an important step towards being able to do the same thing in humans, they reported on Wednesday.

Shoukhrat Mitalipov and colleagues at Oregon Health & Science University said they used skin cells from monkeys to create cloned embryos, and then extracted embryonic stem cells from these days-old embryos.

This had only been done in mice before, they reported in the journal Nature. Mitalipov had given sketchy details of his work at a conference in Australia in June, but the work has now been independently verified by another team of experts.

Friday
Feb232007

Intervention: Genetic Pollution, Smart Breeding and the Risks of Unregulated Transgenesis.

Article PhotoAs a kid in the 70's, I remember walking the shores of Lake Michigan and dodging the rotting piles of dead fish covered in maggots.

These small, silver fish, called alewives, grew in unchecked mega-pods because of the lack of a top predator in the lakes. Lake trout were essentially wiped out around the same time by overfishing and the invasion of the exotic, rapacious sea lamprey. For a time, alewives, which often exhibit seasonal die offs, washed up in putrid layers on the shorelines of the Great Lakes.

There was (and is) a crazy cascade of invasive species that were intentionally introduced to solve the problem. Each intentional introduction of a foreign species creates a new ecological issue that permanently altered the ecology of the Great Lakes. The most recent intruder? Massive Asian carp that can grow to be 80 to 100 pounds. They're ravenous eaters, consuming up to 40 percent of their own body weight in plankton each day. And they're bullies, pushing out weaker, native species. (Listen to NPR story.)

So... the prospect of having genetically modified organisms and micro-organisms invade my personal ecology fills me with dread. Even if measures of accountability are imposed, once the damage is done, there is no point of return.
The latest book by science writer, Denise Caruso, details the threats of introducing new organisms--whether on the nano, the micro and the macro-levels--into the fragile ecology of our planet. Ecological catastrophes that would dwarf the breech of New Orleans' levees.

These potential disasters would, in the words of Caruso, "create stewardship challenges for generations into the future that are already far beyond our present scientific knowledge or capabilities."

From Worldchanging:

Denise Caruso holds a somewhat legendary status among tech journalists. A columnist for the NY Times (her old Information Industries column was a must-read for years, while her new column Re:Framing just kicked off on a bang with a piece titled Someone (Other Than You) May Own Your Genes) and founder of the Hybrid Vigor Institute (an NGO dedicated to facilitating interdisciplinary and collaborative approaches to scientific problem solving), it's not going too far to say that Caruso's work has helped shape our society's thinking about the future of science.

That future may be riskier than we like to think. In her new book, Intervention: Confronting the Real Risks of Genetic Engineering and Life on a Biotech Planet, Caruso lays out in chilling detail exactly why even (perhaps especially) those of us who are strong supporters of science and innovation ought to be extremely concerned about the unintended consequences of contemporary biotechnological industrial research.